Tuna

Overview
Tuna is a lean fish providing omega-3 fatty acids (primarily EPA and DHA), vitamin B3 (niacin), selenium, and highly digestible protein. Marine long-chain omega-3s are a constituent of tuna flesh; reviews of those fatty acids in brain development and function provide constituent-level context rather than a tuna feeding trial [1]. Compared with oily fish such as salmon or mackerel, tuna is lower in total fat but still contributes marine omega-3s and micronutrients in relatively low-calorie portions.
Within the BRAIN Diet framework, tuna is used as one component of a broader fish rotation rather than the sole marine protein source. Niacin-rich foods such as tuna contribute to NAD⁺-dependent metabolic pathways, while selenium participates in glutathione peroxidase and other antioxidant enzymes. Because larger tuna species can accumulate higher levels of mercury, emphasis is placed on choosing lower-trophic species and moderating frequency within an overall pattern that includes smaller oily fish like sardines and herring.
Key Nutritional Highlights
- Highest protein among BRAIN Diet fish and seafood pages (per 100 g).
- Provides complete, highly digestible protein.
- Commonly contributes selenium, iodine, and vitamin B12, though levels vary by species.
- EPA/DHA content is highly species-dependent; oily fish are usually higher than lean fish or shellfish.
- Often lower in saturated fat than many fatty red-meat patterns when minimally processed.
- Nutritional profile and risk context depend on processing method (fresh vs salted/smoked/cured).
Advanced Nutrition
Amino acids
Tuna supplies cystine, which contributes to cysteine availability. This raw bluefin contains 250 mg per 100 g, about 213 mg in 85 g (3 oz). On that raw weight it is a relatively rich cystine source.
Food-composition values are representative, not fixed. Variety, preparation and source can change the amount.
Food Context
Sourcing
- Prefer smaller tuna species (such as skipjack) and products from fisheries with transparent sustainability and contaminant monitoring, as larger predatory tuna tend to accumulate more mercury.
- When using canned tuna, choose products packed in water or high-quality oils without excessive sodium or additives.
Preparation
- Use gentle cooking methods (light searing, baking, steaming) to preserve moisture and omega-3 content; avoid repeated deep-frying or heavy charring.
- Incorporate tuna into meals that also contain vegetables and whole grains, so it contributes lean protein, niacin, and selenium within a balanced plate rather than dominating total dietary fish intake.
Essential Amino Acid Profile
This food provides a complete essential amino acid profile typical of animal proteins, with high digestibility and bioavailability.
Recipes
Nutrient Tables (per 100 g)
Selected food and preparation: Fish, tuna, fresh, bluefin, raw. per 100 g edible portion.
Core nutrients
| Nutrient | Amount per 100 g | % reference intake per 100 g |
|---|---|---|
| Energy | 144 kcal | — |
| Protein | 23.3 g | — |
| Total fat | 4.9 g | — |
| Saturated fat | 1.3 g | — |
Key vitamins and minerals
Vitamins and minerals supplying at least 10% of an adult reference intake per 100 g, derived from the composition panel.
| Nutrient | Amount per 100 g | % reference intake per 100 g |
|---|---|---|
| Magnesium | 50 mg | 11.9% |
| Phosphorus | 254 mg | 36.3% |
| Selenium | 36.5 µg | 66.4% |
| Choline | 65 mg | 11.8% |
| Vitamin B12 | 9.4 µg | 392.9% |
| Vitamin B6 | 0.5 mg | 35% |
| Vitamin B2 | 0.3 mg | 19.3% |
| Vitamin B1 | 0.2 mg | 20.1% |
| Vitamin B3 | 8.7 mg | 54.1% |
| Vitamin B5 | 1.1 mg | 21.1% |
| Vitamin A | 655 µg | 72.8% |
| Vitamin D | 5.7 µg | 38% |
Bioactive compounds
Content applies to the food and preparation identified in the source notes.
| Compound / class | Amount per 100 g | Notes |
|---|---|---|
| EPA | 283 mg | — |
| DHA | 890 mg | — |
Substances
References
[1] McNamara & Carlson (2006). Omega-3 fatty acids in brain development, function, and psychopathology. Constituent-level review of long-chain omega-3 fatty acids in brain development and function; not a tuna feeding trial.





