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Extra Virgin Olive Oil

Extra Virgin Olive Oil

Overview

Extra virgin olive oil (EVOO) is a cornerstone fat in the BRAIN Diet, providing mostly monounsaturated fat (oleic acid) together with meaningful amounts of vitamin E (alpha-tocopherol), vitamin K₁, and a dense cluster of olive-specific polyphenols. While its basic macronutrient profile looks simple, phenolics such as oleuropein aglycone, oleocanthal, oleacein, and hydroxytyrosol derivatives give EVOO a distinctive antioxidant and anti-inflammatory signature compared with refined seed oils [1,2]. The same polyphenol and tocopherol cluster helps stabilise the oil against oxidation during storage and moderate heat cooking.

Within the BRAIN Diet framework, the brain-relevant benefits of EVOO come primarily from these polyphenols and fat-soluble antioxidants rather than from calories or fat alone. The EFSA-authorised claim for “protection of blood lipids from oxidative stress” requires at least 250 mg/kg of hydroxytyrosol and its derivatives (≈25 mg/100 g) [3]. In practice, many commercial EVOOs fall around ~100–250 mg/kg total phenolics, while early-harvest, high-polyphenol oils can reach ~500–900 mg/kg depending on cultivar, harvest timing, and processing [4]. Used as the default dressing and cooking fat around vegetables, legumes, and whole grains, EVOO helps improve polyphenol bioavailability and supports cardiometabolic and neuroprotective mechanisms as part of a Mediterranean-style pattern [2–4].

Food Context

Preparation

  • Best used for salad dressings, drizzling, low-heat cooking to preserve polyphenols
  • Avoid high-heat cooking to preserve polyphenols and prevent oxidation
  • Early harvest oils have higher bioactive content (oleuropein, polyphenols) and may contain CoQ10 in useful quantities
  • Store away from heat and light to preserve antioxidant properties

Recipes

5 recipes containing this food

Roast Duck Breast with Berry Sauce

A rich main dish built around crisp-skinned duck breast with a bright blueberry and raspberry sauce, designed to balance richness with acidity and aromatic depth.

Nutrient Tables (per 100 g)

Core nutrients

NutrientAmount per 100 g% RDA per 100 g
Energy800 kcal
Protein0 g
Total fat93.3 g
Saturated fat13.3 g
Carbohydrates0 g

Key micronutrients

NutrientAmount per 100 g% RDA per 100 g
Vitamin E14.4 mg96%
Vitamin K60 µg50%

Bioactive compounds

Values below are often from specialist compositional databases or literature, not the standard USDA panel. Asterisks (*) refer to source notes at the bottom of this section.

Compound / classAmount per 100 gNotes
Total olive polyphenols15 mg *“Typical” EVOO band; early-harvest / high-phenolic oils can be several-fold higher.
Hydroxytyrosol1.4 mg *EFSA claim threshold is expressed as hydroxytyrosol equivalents (derivatives included).
Tyrosol1 mg *Often co-varies with hydroxytyrosol derivatives across cultivars.
Oleocanthal7.8 mg *Secoiridoid linked to throat “pungency”; concentrations vary widely by oil.
Oleacein4.2 mg *Common secoiridoid in EVOO; correlates with polyphenol-rich chemotypes.
Oleuropein5 mg *Reporting depends on whether aglycones/derivatives are pooled vs split.

Note: Bioactive-compound values vary substantially by cultivar, species, cocoa or oil percentage, processing, and brand formulation. Show quantitative values only where a defensible source exists; otherwise prefer qualitative presence statements or ranges in source notes.

Source notes (bioactive / supplementary):
  • * Total olive polyphenols: Total phenolics in extra virgin olive oil vary widely by cultivar, harvest stage, and processing. A practical "typical EVOO" range is ~100–250 mg/kg (≈10–25 mg/100 g), while high-phenolic/early-harvest oils can reach ~500–900 mg/kg (≈50–90 mg/100 g). Use this row as a guide, not a precise fixed value for all oils.
  • * Hydroxytyrosol: Hydroxytyrosol in EVOO is typically reported in the low mg/kg range and is present largely as derivatives; indicative values across oils are roughly ~7–21 mg/kg (≈0.7–2.1 mg/100 g). The EFSA-authorised claim is based on hydroxytyrosol and its derivatives at ≥250 mg/kg (25 mg/100 g) expressed as hydroxytyrosol equivalents.
  • * Tyrosol: Tyrosol is typically in the low mg/kg range and often co-varies with hydroxytyrosol derivatives; indicative values are roughly ~6–15 mg/kg (≈0.6–1.5 mg/100 g), with substantial variability by cultivar and harvest.
  • * Oleocanthal: Oleocanthal is a major secoiridoid associated with pungency. In an analysis of 100 EVOO samples, mean oleocanthal concentration was ~77.9 mg/kg (≈7.8 mg/100 g), with wide variability across oils.
  • * Oleacein: Oleacein is commonly abundant in EVOO and varies strongly by cultivar and processing. In an analysis of 100 EVOO samples, mean oleacein concentration was ~41.8 mg/kg (≈4.2 mg/100 g); some oils can be much higher.
  • * Oleuropein: Oleuropein-related secoiridoids dominate the phenolic fraction; reported values depend on whether aglycone/derivatives are quantified separately. Use this as a qualitative guide within the broader phenolic range rather than a universal fixed number.
Reference intakes: US Dietary Reference Intakes for adults (19–50 years; using the higher of male/female values where they differ).
Data provenance (core / micronutrient panel): USDA FoodData Central, EXTRA VIRGIN OLIVE OIL, FDC ID 1908563, API, per 100 g edible portion, last checked 2026-03-14

Substances

Substances in this food: editorial (Overview / literature) plus analytical (nutrition table).

8 substances in this food

Oleacein

Secoiridoid polyphenol in extra-virgin olive oil; antioxidant and NRF2 activation

Oleocanthal

Secoiridoid polyphenol in extra-virgin olive oil; NF-κB inhibition and anti-inflammatory effects

Oleuropein

Major secoiridoid polyphenol in olive oil; oleuropein aglycone supports mitophagy, SIRT1, and AMPK activation

Tyrosol

Phenolic compound in olive oil; neuroprotective effects and precursor to hydroxytyrosol

Vitamin K
Total olive polyphenols

References

These references link to the BRAIN Diet bibliography page, where the full citation and DOI/external source link are provided.

  1. Schwingshackl and Hoffmann 2014 – Monounsaturated fatty acids, olive oil and health status
  2. Fielding et al. 2005 – Increases in plasma lycopene after tomatoes cooked with olive oil
  3. EFSA NDA Panel 2011 – Health claims related to polyphenols in olive oil (LDL oxidation)
  4. Pedan et al. 2019 – Phenolic compounds and sensory properties of olive oil (oleocanthal/oleacein means)