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Black Bean & Sweet Potato Vegetable Chilli

Black Bean & Sweet Potato Vegetable Chilli

Overview

A hearty bean and vegetable chilli built around black beans, sweet potato, and mixed vegetables. This dish combines fibre, plant protein, and warming spices to support steady energy and satiety. Ideal for batch cooking and adaptable to different dietary preferences.

Ingredients (4–6 servings)

Base

  • 2 tbsp extra virgin olive oil
  • 1 small onion, finely diced
  • 2 garlic cloves, minced

Vegetables

  • 1 medium sweet potato, grated or finely diced
  • 1 carrot, grated
  • ½ courgette (zucchini), grated
  • 1 red bell pepper, diced

Protein & sauce

  • 2 × 400 g cans black beans, drained and rinsed
  • 3 tbsp tomato purée
  • 250 ml vegetable stock

Spices

  • 1 tbsp smoked paprika
  • 1 tbsp ground cumin
  • 1 tbsp ground coriander
  • Chilli powder or fresh chilli, to taste

Seasoning

  • Salt and black pepper, to taste

Optional to serve

  • Fresh coriander (cilantro)
  • Lime wedges
  • Plain yoghurt or plant yoghurt
  • Cooked quinoa or brown rice

Method

  1. Heat olive oil in a large saucepan over medium heat. Add onion and cook until softened, about 3–5 minutes.
  2. Stir in garlic and cook briefly until fragrant.
  3. Add sweet potato, carrot, courgette, and bell pepper. Cook for 3–5 minutes, stirring to combine.
  4. Add black beans, tomato purée, stock, and spices. Stir well.
  5. Bring to a gentle simmer, cover, and cook 30–40 minutes, stirring occasionally, until vegetables are tender and flavours develop.
  6. Season to taste. Adjust thickness with a splash of water or stock if needed.

Serve warm with optional yoghurt, herbs, lime, or whole grains.

Extra Guidance

  • Refrigerates well for up to 3 days.
  • Freezes successfully for future meals.
  • Flavour deepens after resting, making it ideal for batch preparation.

Nutrition (approximate, per serving)

Based on 4 servings.

  • Energy: ~350–400 kcal
  • Protein: ~10–12 g per serving (4 servings); black beans provide most of the plant protein (~8 g per 100 g cooked)
  • Carbohydrates: ~55–65 g (from beans, sweet potato, vegetables)
  • Fat: ~8–10 g
  • Fibre: ~14–18 g

Brain Health Notes

  • Black beans are high in plant protein (~8 g per 100 g cooked) and provide fibre that feeds gut bacteria; fibre fermentation produces short-chain fatty acids (SCFAs) associated with gut health. Beans also supply folate and minerals.
  • Sweet potato and carrots provide beta-carotene and fibre studied for antioxidant and vascular effects.
  • Bell peppers and tomatoes contribute vitamin C and carotenoids.
  • Extra virgin olive oil contributes monounsaturated fats and polyphenols associated with cardiovascular and brain health.
  • Whole grains (quinoa or brown rice) provide slow-digesting carbohydrates and fibre.

Foods/Substances

12 foods in this recipe

Cilantro

Herb with potential heavy metal chelation properties

Biological Target Matrix

Gut–Brain Axis & Enteric Nervous System (ENS)

SubstanceFoodsMechanism of Action
AcetateByproduct of fibre fermentation; supports intestinal barrier integrity; regulates immune responses; promotes synthesis of key neurotransmitters such as dopamine and serotonin
ButyrateByproduct of fibre fermentation; supports intestinal barrier integrity; regulates immune responses; promotes synthesis of key neurotransmitters such as dopamine and serotonin
CholineCholine is metabolised by gut bacteria; some strains (e.g. Lactobacillus) can produce acetylcholine. Microbial choline metabolism (e.g. trimethylamine) shows inter-individual variability and may influence host metabolism and gut–brain signalling.
PropionateByproduct of fibre fermentation; supports intestinal barrier integrity; regulates immune responses
Short-Chain Fatty Acids (SCFAs)Byproducts of fibre fermentation; support intestinal barrier integrity; regulate immune responses; promote synthesis of key neurotransmitters such as dopamine and serotonin

Inflammation & Oxidative Stress

SubstanceFoodsMechanism of Action
CholineCholine-derived betaine supports homocysteine remethylation; elevated homocysteine is linked to oxidative stress and inflammatory signalling. Phosphatidylcholine supports membrane integrity and cell signalling in immune and redox contexts.

Metabolic & Neuroendocrine Stress (HPA Axis & ANS)

SubstanceFoodsMechanism of Action
CholineCholine supports hepatic VLDL assembly and lipid export; methyl donors (choline, betaine) may influence adenosine metabolism and HPA axis activity. Adequate choline status supports metabolic stability and stress physiology.
MagnesiumHelps manage stress responses; combined with vitamin D reduced behavioral problems; synergy with zinc and omega-3s reported
Quercetin (and Isoquercetin)Contributes to LPS and immune defense; supports stress response modulation
Vitamin B5 (Pantothenic Acid)Supports stress response through energy metabolism and ATP production
Vitamin C (Ascorbate)Supports stress response through antioxidant and neurochemical effects

Methylation & One-Carbon Metabolism

SubstanceFoodsMechanism of Action
CholinePrecursor to trimethylglycine (TMG/betaine), a dietary methyl donor that helps recycle homocysteine to methionine via an alternative pathway; supports one-carbon metabolism alongside folate, riboflavin, and B12; influences methylation dynamics relevant to MTHFR and COMT activity
MethionineEssential amino acid that forms S-adenosylmethionine (SAMe), the universal methyl donor for neurotransmitter synthesis and membrane phospholipid methylation
Vitamin B12 (Cobalamin)Essential cofactor in remethylation of homocysteine to methionine, which is converted to S-adenosylmethionine (SAMe); works with B6, B2, and folate; contributes meaningfully to homocysteine reduction, especially in combination with omega-3 fatty acids
Vitamin B2 (Riboflavin)FAD acts as a critical cofactor for MTHFR, linking riboflavin to homocysteine recycling and methylation capacity
Vitamin B6 (Pyridoxine → PLP)Essential cofactor in remethylation of homocysteine to methionine, which is converted to S-adenosylmethionine (SAMe); works with B2, folate, and B12
Vitamin B9 (Folate; 5-MTHF)Essential cofactor in remethylation of homocysteine to methionine, which is converted to S-adenosylmethionine (SAMe); SAMe fuels synthesis of dopamine, norepinephrine, and serotonin and drives phospholipid methylation in neuronal membranes
ZincDeficiencies in vitamins and minerals essential for methylation, such as folate, vitamin B12, and zinc, are correlated to ADHD symptoms; supplementing these micronutrients has shown potential in supporting methylation and reducing symptom severity

Mitochondrial Function & Bioenergetics

SubstanceFoodsMechanism of Action
ButyrateSupports mitochondrial function, enhancing brain energy metabolism; aids in reducing cholesterol and neuroinflammation
CholinePhosphatidylcholine and other choline-containing phospholipids support mitochondrial membrane integrity and energy metabolism; choline-derived betaine contributes to one-carbon status that can influence mitochondrial resilience
IronCritical for oxygen delivery to the brain via hemoglobin; supports mitochondrial function and energy production
MagnesiumSupports enzymes involved in glycolysis and the Krebs cycle (processes that generate ATP from glucose); binds to ATP and all triphosphates in cells to activate them
ManganeseSupports mitochondrial antioxidant defense through MnSOD activity
OleuropeinOleuropein aglycone (the active form) supports mitophagy, SIRT1 activation, and AMPK activation; enhances mitochondrial function, autophagy, and neuroprotective effects through modulation of mitochondrial dynamics and antioxidant pathways
Quercetin (and Isoquercetin)Enhances mitochondrial baseline activity and energy production; supports mitochondrial function
Short-Chain Fatty Acids (SCFAs)Butyrate supports mitochondrial function, enhancing brain energy metabolism; aids in reducing cholesterol and neuroinflammation
Vitamin B1 (Thiamine)Essential for mitochondrial glucose metabolism in the brain leading to ATP production; supports PDH (pyruvate dehydrogenase) and α-KGDH (alpha-ketoglutarate dehydrogenase) function
Vitamin B12 (Cobalamin)Crucial role in conversion of methylmalonyl-CoA to succinyl-CoA, a key step in mitochondrial energy production; deficiency leads to buildup of methylmalonic acid and odd-chain fatty acids, which are neurotoxic
Vitamin B2 (Riboflavin)Forms FMN/FAD coenzymes, supporting oxidative metabolism and redox balance; facilitates metabolism of B12, B6, and niacin; supports antioxidant enzymes
Vitamin B5 (Pantothenic Acid)Forms CoA (coenzyme A), required for β-oxidation and TCA cycle acetyl-CoA flux; deficiency impairs ATP production impacting brain energy

Neurotransmitter Regulation

SubstanceFoodsMechanism of Action
CalciumEssential for nerve impulse transmission and neurotransmission
CholineEssential precursor for acetylcholine synthesis, supporting memory, learning, and neuroplasticity; supports membrane phospholipid biosynthesis (PC) which is critical for membrane fluidity and neurotransmitter receptor function; phospholipid methylation (PLM) alters membrane structure, facilitating faster neuronal recovery and influencing ion channel behavior in gamma oscillations linked to attention and cognition
CopperCofactor in dopamine β-hydroxylase, supporting catecholamine synthesis; supports norepinephrine synthesis
IronEssential cofactor for tyrosine hydroxylase, the rate-limiting enzyme in the conversion of tyrosine to dopamine; critical for catecholamine synthesis
MagnesiumBroad cofactor for neurotransmitter synthesis and receptor modulation (e.g., NMDA, GABA); functions as an NMDA receptor antagonist and GABA receptor modulator; assists enzymes involved in synthesis of dopamine and serotonin
PhenylalanineEssential amino acid that converts to tyrosine and supports catecholamine synthesis (dopamine, norepinephrine); participates in LAT1 competition at the blood-brain barrier
PotassiumCritical for membrane potential, nerve signaling, and neuronal excitability; adequate intake balances sodium effects
PropionateStimulates secretion of norepinephrine and may influence dopamine regulation; promotes synthesis of key neurotransmitters
Short-Chain Fatty Acids (SCFAs)Propionate stimulates secretion of norepinephrine and may influence dopamine regulation; SCFAs promote synthesis of dopamine and serotonin
TryptophanPrecursor for serotonin and melatonin; brain entry competes at LAT1 with other large neutral amino acids (LNAAs); carbohydrate-rich, low-protein meals raise the plasma tryptophan:LNAA ratio because insulin pushes competing LNAAs out to muscles; can feed NAD+ synthesis via the kynurenine pathway
TyrosineCatecholamine precursor (dopamine, norepinephrine); brain transport via LAT1 competes with other LNAAs; iron is an essential cofactor for tyrosine hydroxylase, the rate-limiting enzyme in conversion of tyrosine to dopamine; cofactors include iron, B6, folate, omega-3s, and BH₄ (tetrahydrobiopterin) to support rate-limiting steps in catecholamine synthesis
TyrosolNeuroprotective effects; contributes to brain health benefits of extra-virgin olive oil
Vitamin B12 (Cobalamin)Supports neurotransmitter production through methylation; essential for myelin synthesis
Vitamin B6 (Pyridoxine → PLP)Cofactor for synthesis of dopamine, serotonin, GABA, and glutamate; supports rate-limiting steps in catecholamine synthesis; requires PDXK activation with magnesium and ATP support
Vitamin B9 (Folate; 5-MTHF)Supports neurotransmitter synthesis through methylation; cofactor for dopamine synthesis alongside iron, B6, and omega-3s
Vitamin C (Ascorbate)Supports norepinephrine synthesis; transported in brain via SVCT2
ZincImportant for DNA synthesis, cell division, and neurotransmitter regulation, particularly in modulating dopamine—a key neurotransmitter implicated in ADHD; acts as an allosteric modulator of the GABA receptor; supports glutamate regulation