Nutritional Yeast

Overview

Nutritional yeast, especially fortified varieties, provides B12, B6, and nicotinamide riboside (NAD+ precursor), helping close vegan nutrient gaps. Fortified nutritional yeast (B12, B6) helps narrow vegan nutrient gaps, and precision sourcing of functional plant foods such as Mankai duckweed (iron, B12), soy/soy lecithin (choline), and fortified nutritional yeast (B12, B6) is recommended.

Recipes

no recipes found

Substances

2 substances in this food

Vitamin B12 (Cobalamin)

Methylation; myelin; mitochondrial odd-chain FA metabolism

Vitamin B6 (Pyridoxine → PLP)

PLP cofactor for neurotransmitter synthesis; relies on brain PDXK activation

Preparation Notes

• Choose fortified varieties for B12
• Can be used as seasoning or supplement
• Important for vegan/vegetarian diets
• Part of functional food strategy

Biological Target Matrix

Biological Target	Substance	Therapeutic Areas	Mechanism of Action
Methylation	Vitamin B12 (Cobalamin)	ADHD, Anxiety & GAD, Depression & MDD, Alzheimer's Disease	Essential cofactor in remethylation of homocysteine to methionine, which is converted to S-adenosylmethionine (SAMe); works with B6, B2, and folate; contributes meaningfully to homocysteine reduction, especially in combination with omega-3 fatty acids
Methylation	Vitamin B6 (Pyridoxine → PLP)	ADHD, Anxiety & GAD, Depression & MDD, Alzheimer's Disease	Essential cofactor in remethylation of homocysteine to methionine, which is converted to S-adenosylmethionine (SAMe); works with B2, folate, and B12
Mitochondrial Support	Vitamin B12 (Cobalamin)	ADHD, Anxiety & GAD, Depression & MDD, Alzheimer's Disease, Bipolar Disorder	Crucial role in conversion of methylmalonyl-CoA to succinyl-CoA, a key step in mitochondrial energy production; deficiency leads to buildup of methylmalonic acid and odd-chain fatty acids, which are neurotoxic
Neurochemical Balance	Vitamin B12 (Cobalamin)	ADHD, Anxiety & GAD, Depression & MDD, Alzheimer's Disease, Bipolar Disorder	Supports neurotransmitter production through methylation; essential for myelin synthesis
Neurochemical Balance	Vitamin B6 (Pyridoxine → PLP)	ADHD, Anxiety & GAD, Depression & MDD, Alzheimer's Disease, Bipolar Disorder	Cofactor for synthesis of dopamine, serotonin, GABA, and glutamate; supports rate-limiting steps in catecholamine synthesis; requires PDXK activation with magnesium and ATP support

References

• Fortified nutritional yeast (B12, B6) helps narrow vegan nutrient gaps
• Precision sourcing of functional plant foods such as Mankai duckweed (iron, B12), soy/soy lecithin (choline), and fortified nutritional yeast (B12, B6)
• Targets foods providing essential brain supporting vitamins: D (UV-exposed mushrooms; fortified plant milks/yogurts), B12 (fortified plant milks, nutritional yeast)
• Nicotinamide Riboside: Dairy milk, whey protein, yeast-containing foods (e.g., sourdough bread)