Coffee

Overview
Coffee provides caffeine, a adenosine-receptor antagonist that increases striatal dopamine D2/D3 receptor availability and acute alertness [1]. Coffee polyphenols contribute to dietary flavonoid intake [2].
Within the BRAIN Diet framework, coffee is a polyphenol beverage used morning-to-midday; caffeine timing affects sleep — stop ~8 hours before bed if sensitive [1]. Avoid taking with iron-rich plant meals if optimising non-heme iron absorption.
Key Nutritional Highlights
- Caffeine modulates dopamine receptor availability and alertness [1].
- Chlorogenic-acid polyphenols add flavonoid intake [2].
- Timing matters for sleep; individual caffeine metabolism varies.
- Unsweetened brews only; polyphenol–iron absorption competition with meals.
Food Context
Preparation
- Stop 8+ hours before bed (variable half-life)
- Can stimulate dopamine but may cause fatigue rebound
- Space ≥1 hour from iron-rich meals or add lemon
- Strategic, sparing use may be most effective for ADHD
Recipes
Nutrient Tables (per 100 g)
Core nutrients
| Nutrient | Amount per 100 g | % RDA per 100 g |
|---|---|---|
| Energy | 2 kcal | — |
| Protein | 0.3 g | — |
| Carbohydrates | 0.2 g | — |
Bioactive compounds
Explicitly identified compounds, including individual fatty acids, with a defensible quantity or an explicit qualitative status. Asterisks (*) identify supplementary sources below. Unquantified or trace constituents are not automatically admitted to the Substances list.
| Compound / class | Amount per 100 g | Notes |
|---|---|---|
| Polyphenols | Present — quantity not established * | — |
- * Polyphenols: Coffee is a dietary source of chlorogenic acids and related polyphenols; USDA SR Legacy does not report total polyphenols for brewed coffee.
Substances
References
[1] Caffeine modulates dopamine receptor availability and alertness. Volkow & Wang 2015. Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain
[2] Chlorogenic-acid polyphenols add flavonoid intake. Neshatdoust & Saunders 2016. High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials