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Coffee

Overview​

Coffee provides caffeine that stimulates dopamine production but has pendulum effects and circadian disruption risks, requiring strategic use. Caffeine is an adenosine receptor antagonism and should be stopped 8 hours before bed considering caffeine has a highly variable half-life, ranging from 2 to 10 h, but possibly up to 20 hours.

Recipes​

no recipes found

Substances​

no substances found

Preparation Notes​

  • Stop 8+ hours before bed (variable half-life)
  • Can stimulate dopamine but may cause fatigue rebound
  • Space ≥1 hour from iron-rich meals or add lemon
  • Strategic, sparing use may be most effective for ADHD

Biological Target Matrix​

No biological targets found for food: Coffee

References​

  • Caffeine is an adenosine receptor antagonism; stop 8 hours before bed considering caffeine has a highly variable half-life, ranging from 2 to 10 h, but possibly up to 20 hours
  • Caffeine can reverse the deficits associated with fatigue it can be implicated in causing the fatigue in the first place
  • Caffeine increases striatal dopamine D2/D3 receptor availability
  • Polyphenol-rich beverages (tea/coffee) can reduce non-heme iron absorption