Grapes

Overview
Grapes provide resveratrol, a polyphenol that activates SIRT1, enhancing NAD+-dependent processes and supporting mitochondrial function. Red and purple grape varieties additionally supply anthocyanins built on Malvidin, Cyanidin, Delphinidin, Peonidin, and Petunidin backbones (green/white grapes contribute little anthocyanin).
Within the BRAIN Diet framework, polyphenols (e.g., resveratrol) activate SIRT1, enhancing NAD⁺-dependent processes, and are found in grapes, blueberries, cranberries, peanuts, and dark chocolate.
Food Context
Synergies
- Part of diverse polyphenol intake
- Pair with other resveratrol sources
Preparation
- Can be consumed fresh or as juice (whole fruit preferred)
- Supports mitochondrial NAD+ pathways
Recipes
Nutrient Tables (per 100 g)
Selected food and preparation: Grapes, red or green (European type, such as Thompson seedless), raw. per 100 g edible portion.
Core nutrients
| Nutrient | Amount per 100 g | % reference intake per 100 g |
|---|---|---|
| Energy | 69 kcal | — |
| Protein | 0.7 g | — |
| Total fat | 0.2 g | — |
| Saturated fat | 0.1 g | — |
| Carbohydrates | 18.1 g | — |
| Sugars | 15.5 g | — |
| Fibre | 0.9 g | — |
Key vitamins and minerals
Vitamins and minerals supplying at least 10% of an adult reference intake per 100 g, derived from the composition panel.
| Nutrient | Amount per 100 g | % reference intake per 100 g |
|---|---|---|
| Copper | 0.1 mg | 14.1% |
| Vitamin K | 14.6 µg | 12.2% |
Bioactive compounds
| Compound / class | Amount per 100 g | Notes |
|---|---|---|
| Cyanidin | Present — quantity not established | Grapes, red, raw; NDB 97074 — glycosides / reported aglycone equivalents |
| Delphinidin | Present — quantity not established | Grapes, red, raw; NDB 97074 — glycosides / reported aglycone equivalents |
| Malvidin | Present — quantity not established | Grapes, red, raw; NDB 97074 — glycosides / reported aglycone equivalents |
| Peonidin | Present — quantity not established | Grapes, red, raw; NDB 97074 — glycosides / reported aglycone equivalents |
| Petunidin | Present — quantity not established | Grapes, red, raw; NDB 97074 — glycosides / reported aglycone equivalents |
- Cyanidin, Delphinidin, Malvidin, Peonidin, Petunidin: USDA flavonoid database, Release 3.3; the studied food form is shown beside each constituent. Glycoside-derived records do not establish free-aglycone amounts.
Technical provenance
Cyanidin: USDA flavonoid database Release 3.3 (2018); Printed page 37; Grapes, red, raw; NDB 97074. Positive mean in the named food row, not an assumed association from database title. No free-aglycone mass inferred.
Delphinidin: USDA flavonoid database Release 3.3 (2018); Printed page 37; Grapes, red, raw; NDB 97074. Positive mean in the named food row, not an assumed association from database title. No free-aglycone mass inferred.
Malvidin: USDA flavonoid database Release 3.3 (2018); Printed page 37; Grapes, red, raw; NDB 97074. Positive mean in the named food row, not an assumed association from database title. No free-aglycone mass inferred.
Peonidin: USDA flavonoid database Release 3.3 (2018); Printed page 37; Grapes, red, raw; NDB 97074. Positive mean in the named food row, not an assumed association from database title. No free-aglycone mass inferred.
Petunidin: USDA flavonoid database Release 3.3 (2018); Printed page 37; Grapes, red, raw; NDB 97074. Positive mean in the named food row, not an assumed association from database title. No free-aglycone mass inferred.
Substances
References
[1] Polyphenol-rich fruit patterns are associated with cognitive endpoints in flavonoid intervention trials. Neshatdoust et al. 2016. High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials
[2] Grape polyphenols such as resveratrol are studied for antioxidant and nutraceutical mechanisms. Boots et al. 2008. Health effects of quercetin: From antioxidant to nutraceutical