Grapes

Overview
Grapes provide resveratrol, a polyphenol that activates SIRT1, enhancing NAD+-dependent processes and supporting mitochondrial function. Red and purple grape varieties additionally supply anthocyanins built on Malvidin, Cyanidin, Delphinidin, Peonidin, and Petunidin backbones (green/white grapes contribute little anthocyanin).
Within the BRAIN Diet framework, polyphenols (e.g., resveratrol) activate SIRT1, enhancing NAD⁺-dependent processes, and are found in grapes, blueberries, cranberries, peanuts, and dark chocolate [1][2].
Key Nutritional Highlights
- Polyphenol-rich fruit patterns are associated with cognitive endpoints in flavonoid intervention trials [1]
- Grape polyphenols such as resveratrol are studied for antioxidant and nutraceutical mechanisms [2]
- Grapes provide resveratrol, a polyphenol that activates SIRT1, enhancing NAD+-dependent processes and supporting mitochondrial function. [1]
- Polyphenols (e.g., resveratrol) activate SIRT1, enhancing NAD⁺-dependent processes, and are found in grapes, blueberries, cranberries, peanuts, and dark chocolate. [2]
- Grapes provide resveratrol, a polyphenol that activates SIRT1, enhancing NAD+-dependent processes and supporting mitochondrial function.
Food Context
Synergies
- Part of diverse polyphenol intake
- Pair with other resveratrol sources
Preparation
- Can be consumed fresh or as juice (whole fruit preferred)
- Supports mitochondrial NAD+ pathways
Recipes
Nutrient Tables (per 100 g)
Core nutrients
| Nutrient | Amount per 100 g | % RDA per 100 g |
|---|---|---|
| Energy | 69 kcal | — |
| Protein | 0.7 g | — |
| Total fat | 0.2 g | — |
| Saturated fat | 0.1 g | — |
| Carbohydrates | 18.1 g | — |
| Sugars | 15.5 g | — |
| Fibre | 0.9 g | — |
Key vitamins and minerals
| Nutrient | Amount per 100 g | % RDA per 100 g |
|---|---|---|
| Potassium | 191 mg | 5.6% |
Bioactive compounds
Explicitly identified compounds, including individual fatty acids, with a defensible quantity or an explicit qualitative status. Asterisks (*) identify supplementary sources below. Unquantified or trace constituents are not automatically admitted to the Substances list.
| Compound / class | Amount per 100 g | Notes |
|---|---|---|
| Cyanidin | Present — quantity not established * | — |
| Delphinidin | Present — quantity not established * | — |
| Malvidin | Present — quantity not established * | — |
| Peonidin | Present — quantity not established * | — |
| Petunidin | Present — quantity not established * | — |
- * Cyanidin: USDA Database for the Flavonoid Content of Selected Foods (Release 3.3) lists cyanidin glycosides in Grapes; individual cyanidin mass is not reported in the selected USDA SR Legacy composition record.
- * Delphinidin: USDA flavonoid database / Phenol-Explorer list delphinidin glycosides in Grapes; per-100 g of the isolated anthocyanidin is not in the selected USDA SR Legacy record.
- * Malvidin: USDA flavonoid database lists malvidin glycosides in Grapes; individual malvidin quantity is not in the selected USDA SR Legacy record.
- * Peonidin: USDA flavonoid database lists peonidin glycosides in Grapes; individual peonidin quantity is not in the selected USDA SR Legacy record.
- * Petunidin: USDA flavonoid database lists petunidin glycosides in Grapes; individual petunidin quantity is not in the selected USDA SR Legacy record.
Substances
References
[1] Polyphenol-rich fruit patterns are associated with cognitive endpoints in flavonoid intervention trials. Neshatdoust et al. 2016. High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials
[2] Grape polyphenols such as resveratrol are studied for antioxidant and nutraceutical mechanisms. Boots et al. 2008. Health effects of quercetin: From antioxidant to nutraceutical