Oleuropein
Recipes
Foods
Biological Mechanisms and Implications
| Biological Target | Therapeutic Areas | Mechanism of Action |
|---|---|---|
| Inflammation | Anti-inflammatory properties; contributes to neuroprotective effects of extra-virgin olive oil | |
| Mitochondrial Support | Oleuropein aglycone (the active form) supports mitophagy, SIRT1 activation, and AMPK activation; enhances mitochondrial function, autophagy, and neuroprotective effects through modulation of mitochondrial dynamics and antioxidant pathways | |
| Oxidative Stress | Antioxidant polyphenol; works within the polyphenol network in olive oil |
References
- Early harvest extra virgin olive oil with higher levels of CoQ10, oleuropein and polyphenols Gasmi et al. 2022
- Olive oil phenolic compounds, particularly oleuropein and hydroxytyrosol, support mitochondrial function, autophagy, and neuroprotective effects through modulation of mitochondrial dynamics and antioxidant pathways
- Early harvest oils have higher bioactive content (CoQ10, oleuropein, polyphenols)
- The implementation of the BRAIN diet must go beyond a standard nutrient density focus, it's about choosing foods for their specific bioactive potential: early harvest extra virgin olive oil with higher levels of CoQ10, oleuropein and polyphenols




