Lutein
Overview
Lutein is a carotenoid pigment found in dark green leafy vegetables, egg yolks, and other yellow-orange plant foods. It accumulates in neural tissues and the retina, where it provides antioxidant protection and supports visual function. Lutein exhibits neuroprotective properties through its antioxidant and anti-inflammatory effects, helping protect brain cells from oxidative damage. It has been associated with improved cognitive performance, particularly in memory, processing speed, and visual-spatial function. Like other carotenoids, lutein's absorption is enhanced when consumed with dietary fats.
Recipes
Foods
Biological Mechanisms and Implications
| Biological Target | Therapeutic Areas | Mechanism of Action |
|---|---|---|
| Inflammation | Anti-inflammatory properties; supports immune regulation | |
| Oxidative Stress | Antioxidant properties; scavenges reactive oxygen species and stabilizes cell membranes |
References
- Carotenoids, particularly lutein, zeaxanthin, and β-carotene, play a neuroprotective role through their antioxidant and anti-inflammatory properties Johnson 2014
- Lutein and zeaxanthin have been associated with improved cognitive performance, especially in domains such as memory, processing speed, and visual-spatial function Yagi et al. 2021 Lieblein-Boff et al. 2015 Vishwanathan et al. 2014
- The bioaccessibility of carotenoids in vegetables is remarkably low—only 1-3% of the β-carotene in raw carrots is accessible for absorption Fielding et al. 2005
- Co-consuming a small amount of unsaturated fat with polyphenol-rich foods improves micelle formation and chylomicron packaging, increasing carotenoid absorption Kindel et al. 2010 Brown et al. 2004




