Allicin

Overview
Allicin is a reactive sulfur compound formed from alliin when garlic tissue is damaged, through the enzyme alliinase [1]. The substance page concerns allicin itself; garlic, extracts and other sulfur compounds require their own evidence attribution. Preparation therefore matters when describing exposure.
Its reactions with glutathione and protein thiols help explain activity in experimental systems [1]. Such chemistry does not independently establish a dietary benefit, a brain effect, or an effective human intake. Findings for a garlic product cannot be assigned to allicin alone without evidence that isolates its contribution.
Dietary Context
Garlic tissue damage enables alliin → allicin formation [1]. Precursor content and formed allicin are separate measurements.
Research Spotlights & Evidence Checks
Foods
Recipes
Biological Regulatory Systems
| Biological Regulatory System | Evidence-qualified relationship | Evidence |
|---|---|---|
| Inflammation & Oxidative Stress (BRS3) | Thiol-reactive chemistry; mechanistic relevance rather than demonstrated dietary efficacy | [1] |
References
[1] Borlinghaus et al. (2014). Allicin: chemistry and biological properties. Formation and redox chemistry review.



