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Vitamin B2 (Riboflavin)

Overview

Vitamin B2, also known as riboflavin, is a water-soluble vitamin that forms the coenzymes FMN (flavin mononucleotide) and FAD (flavin adenine dinucleotide). These coenzymes support oxidative metabolism and redox balance throughout the body. FAD acts as a critical cofactor for MTHFR (methylenetetrahydrofolate reductase), linking riboflavin to homocysteine recycling and methylation capacity. Riboflavin also facilitates the metabolism of other B vitamins including B12, B6, and niacin, and supports antioxidant enzymes, making it an important component of the B vitamin network.

Recipes

12 recipes containing this substance

Chocolate Quinoa Crisp Clusters

A delicious cereal-to-snack hybrid with satisfying crunch, steady energy, and a low glycemic profile. Perfect for breakfast or anytime snacking.

Creamed Corn on Roasted Sweet Potato

Roasted sweet potato with creamed corn and a mixed lipid phase to enhance carotenoid absorption; served with broccoli for fibre and glucosinolates.

Ginger Yogurt and Blueberries

A polyphenol-rich breakfast bowl with high fibre, combining ginger, omega-3 nuts, blueberry polyphenols, and probiotic yogurt.

Mitochondrial Power Bowl

A nitrate-rich, polyphenol-dense bowl combining leafy greens, beets, berries, nuts, and early harvest olive oil

Salmon Bowl-pistachio-cacao-nibs

A Mediterranean-style bowl combining salmon, avocado, pistachios, cacao nibs, and early harvest olive oil — rich in omega-3 fats, polyphenols, and fibre.

Turmeric Milk

A warming drink combining turmeric (curcumin) with milk/fat for enhanced curcumin absorption

Foods

10 foods containing this substance

Almonds

Vitamin E, plant protein, and healthy fats

Beef

High creatine, CoQ10, heme iron, and complete protein

Broccoli

Cruciferous vegetable rich in sulforaphane, folate, and glutathione precursors

Eggs

Complete protein with choline, B vitamins, and phospholipids

Kale

Leafy green rich in iron, magnesium, zinc, quercetin, and carotenoids

Milk

Complete protein, nicotinamide riboside, and calcium

Quinoa

Pseudograin with complete protein, magnesium, and GABA potential in sourdough

Salmon

Oily fish rich in EPA/DHA, protein, and B vitamins

Spinach

Leafy green rich in iron, magnesium, folate, and carotenoids

Yogurt

Fermented dairy providing probiotics and complete protein

Biological Mechanisms and Implications

Biological TargetTherapeutic AreasMechanism of Action
Methylation & One-Carbon MetabolismFAD acts as a critical cofactor for MTHFR, linking riboflavin to homocysteine recycling and methylation capacity
Mitochondrial Function & BioenergeticsForms FMN/FAD coenzymes, supporting oxidative metabolism and redox balance; facilitates metabolism of B12, B6, and niacin; supports antioxidant enzymes

References

  • Riboflavin forms FMN/FAD, supporting oxidative metabolism and redox balance; FAD is a critical cofactor for MTHFR, linking B2 to homocysteine recycling and methylation capacity Aragão et al. 2024
  • Riboflavin facilitates metabolism of B12, B6, and niacin; supports antioxidant enzymes; ties into methylation capacity