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Vitamin A (Retinoids; β-Carotene precursor)

Overview

Vitamin A is a fat-soluble vitamin that exists in two main forms: preformed vitamin A (retinoids) from animal sources and provitamin A carotenoids (like β-carotene) from plant sources. Vitamin A is essential for vision, immune function, and neurodevelopment. Provitamin A carotenoids also function as antioxidants in neural tissue, contributing to the antioxidant network that protects brain cells from oxidative damage. The absorption of carotenoids is significantly enhanced when consumed with dietary fats, making food pairing important for maximizing bioavailability.

Recipes

3 recipes containing this substance

Mitochondrial Power Bowl

A nitrate-rich, polyphenol-dense bowl supporting mitochondrial function, ATP generation, and metabolic resilience

Turmeric Lentil Dahl

Anti-inflammatory curcumin-rich lentil dish supporting gut health, NF-κB inhibition, and SCFA production

Foods

10 foods containing this substance

Butter

See grass-fed butter for detailed information

Egg Yolks

Nutrient-dense part of eggs with choline, lutein, and fat-soluble vitamins

Eggs

Complete protein with choline, B vitamins, and phospholipids

Ghee

Heat-stable clarified butter with butyrate and fat-soluble vitamins

Kale

Leafy green rich in iron, magnesium, zinc, quercetin, and carotenoids

Liver

Nutrient-dense organ meat with bioavailable B12, retinol, iron, and CoQ10

Organ Meats

Nutrient-dense offal including liver, heart, kidney

Spinach

Leafy green rich in iron, magnesium, folate, and carotenoids

Swiss Chard

Leafy green rich in iron, magnesium, folate, and carotenoids

Biological Mechanisms and Implications

Biological TargetTherapeutic AreasMechanism of Action
Oxidative StressProvitamin A carotenoids (β-carotene) act as antioxidants in neural tissue; contribute to antioxidant network

References

  • Carotenoids, particularly lutein, zeaxanthin, and β-carotene, play a neuroprotective role through their antioxidant and anti-inflammatory properties Johnson 2014
  • The bioaccessibility of carotenoids in vegetables is remarkably low—only 1-3% of the β-carotene in raw carrots is accessible for absorption Fielding et al. 2005
  • Co-consuming a small amount of unsaturated fat with polyphenol-rich foods improves micelle formation and chylomicron packaging, increasing carotenoid and fat-soluble vitamin absorption Kindel et al. 2010 Brown et al. 2004