Vitamin A (Retinoids; β-Carotene precursor)
Overview
Vitamin A is a fat-soluble vitamin that exists in two main forms: preformed vitamin A (retinoids) from animal sources and provitamin A carotenoids (like β-carotene) from plant sources. Vitamin A is essential for vision, immune function, and neurodevelopment. Provitamin A carotenoids also function as antioxidants in neural tissue, contributing to the antioxidant network that protects brain cells from oxidative damage. The absorption of carotenoids is significantly enhanced when consumed with dietary fats, making food pairing important for maximizing bioavailability.
Recipes
Foods
Biological Mechanisms and Implications
| Biological Target | Therapeutic Areas | Mechanism of Action |
|---|---|---|
| Oxidative Stress | Provitamin A carotenoids (β-carotene) act as antioxidants in neural tissue; contribute to antioxidant network |
References
- Carotenoids, particularly lutein, zeaxanthin, and β-carotene, play a neuroprotective role through their antioxidant and anti-inflammatory properties Johnson 2014
- The bioaccessibility of carotenoids in vegetables is remarkably low—only 1-3% of the β-carotene in raw carrots is accessible for absorption Fielding et al. 2005
- Co-consuming a small amount of unsaturated fat with polyphenol-rich foods improves micelle formation and chylomicron packaging, increasing carotenoid and fat-soluble vitamin absorption Kindel et al. 2010 Brown et al. 2004


