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54 docs tagged with "Bioactive"

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docs > substances > bioactive-compounds > alkaloids

Berberine

Polyphenolic alkaloid; glycemic control; antimicrobial effects; microbiome modulation

L-DOPA

Levodopa: a pharmacologically active precursor of dopamine

L-Theanine

Calming amino acid from tea; increases alpha waves; sleep-friendly

docs > substances > bioactive-compounds

Beta-Glucans

Polysaccharides with immune-modulating properties found in mushrooms and other foods

Glutathione

Endogenous γ-glutamyl-cysteinyl-glycine tripeptide and GSH/GSSG redox resource pool; nutritionally relevant through precursor supply, synthesis and recycling rather than as a vitamin.

N-acetylcysteine

Supplemental cysteine precursor. The glutathione result used it together with glycine in older adults. It is not food cysteine.

Nitrate

Dietary nitrate that converts to nitric oxide, supporting vascular function and mitochondrial efficiency

Polysaccharides

Complex carbohydrates with immune-modulating and gut microbiome supporting properties

Spermidine

A dietary and endogenous polyamine studied in cellular recycling and mitochondrial maintenance; human cognitive benefit remains unestablished.

Taurine

Osmoregulator; GABA modulation; mitochondrial membrane stabilizer; anti-inflammatory

Uridine

Nucleoside that can supply CTP for CDP-choline. UMP and uridine-plus-DHA combinations are separate exposures.

docs > substances > bioactive-compounds > carotenoids

Astaxanthin

Xanthophyll carotenoid in salmon, salmon roe, and related marine foods; mapped to BRS3 redox signalling and BRS4 mitochondrial membrane protection.

β-Carotene

Neuroprotective carotenoid; vitamin A precursor; supports immune regulation and neuronal development

Lutein

Neuroprotective carotenoid; accumulates in neural tissues and retina; supports cognitive performance

Lycopene

Neuroprotective carotenoid; found in tomatoes; absorption enhanced by cooking and dietary fat

Zeaxanthin

Neuroprotective carotenoid; accumulates in neural tissues and retina; supports cognitive performance

docs > substances > bioactive-compounds > choline-methylation

Betaine

Trimethylglycine in beets, spinach, wheat germ and quinoa; methyl donor for BHMT, with brain effects not yet established.

Choline

Essential methyl-donor nutrient in eggs, meat and milk; mapped to BRS2 one-carbon metabolism and BRS6 hepatic lipid export.

docs > substances > bioactive-compounds > lignans

Sesamin

Principal sesame lignan; preliminary cardiometabolic trials, null food-level findings, and incomplete translation to ordinary servings.

Sesamolin

Distinct sesame lignan with redox and neuroprotective laboratory findings and almost no human clinical evidence.

docs > substances > bioactive-compounds > lipid-based

Coenzyme Q10 (CoQ10)

Electron transport chain cofactor and antioxidant relevant to mitochondrial function

Creatine

Phosphocreatine system buffer for neuronal ATP demand; cognitive support evidence

docs > substances > bioactive-compounds > organosulfur

Allicin

Reactive organosulfur compound formed when garlic is crushed; linked to antioxidant and antimicrobial effects.

Glucoraphanin

Glucosinolate precursor of sulforaphane, concentrated in broccoli sprouts.

Sulforaphane

Isothiocyanate formed from glucoraphanin when myrosinase is active; studied for Nrf2 signalling.

docs > substances > bioactive-compounds > polyphenols > anthocyanins

Anthocyanins

Glycosylated flavonoid pigments derived from anthocyanidin parent structures. Human evidence typically concerns anthocyanin-rich foods, mixed extracts, or specific glycosides rather than isolated anthocyanidin aglycones.

Delphinidin

Anthocyanidin parent compound; occurs in foods predominantly as glycosylated anthocyanins.

Malvidin

Anthocyanidin parent compound; occurs in foods predominantly as glycosylated derivatives, notably in red/purple grapes and blueberries.

Pelargonidin

Anthocyanidin parent compound; occurs in foods predominantly as glycosides and is the dominant anthocyanidin backbone in strawberries.

Peonidin

Anthocyanidin parent compound; occurs in foods predominantly as methylated anthocyanin glycosides, including in cherries, cranberries, and blueberries.

Petunidin

Anthocyanidin parent compound; occurs in foods predominantly as glycosylated anthocyanins, including in blueberries and red/purple grapes.

docs > substances > bioactive-compounds > polyphenols > curcuminoids

Curcumin (Turmeric)

Anti-inflammatory, antioxidant; bioavailability enhanced with piperine and fats

docs > substances > bioactive-compounds > polyphenols

Ellagitannins

Hydrolysable tannins that release ellagic acid. They are the upstream class, not ellagic acid and not urolithin A.

docs > substances > bioactive-compounds > polyphenols > flavan-3-ols

Catechin

Cocoa flavanol monomer (a catechin); part of dark chocolate flavanol fraction.

Epicatechin

Cocoa flavanol monomer (a catechin); linked to vascular and cognitive endpoints.

Oligomeric Procyanidins

Dark chocolate procyanidin oligomer fraction (flavanol oligomers); studied as part of total cocoa flavanol profile.

docs > substances > bioactive-compounds > polyphenols > flavanones

Eriocitrin

Lemon-associated citrus flavanone studied for antioxidant activity and flavanone metabolism.

Hesperidin

Citrus flavanone glycoside (notably orange, also present in lemon) with cardiometabolic and vascular research interest.

docs > substances > bioactive-compounds > polyphenols > flavonols

Kaempferol

Dietary flavonol in leafy greens, herbs, tea and some fruits; studied as a food constituent and as an isolated hormetic/senolytic agent.

docs > substances > bioactive-compounds > polyphenols > isoflavones

Genistein

Soy isoflavone; ECS modulation via FAAH inhibition; anti-inflammatory/neuroprotective

docs > substances > bioactive-compounds > polyphenols > phenolic-acids

Ellagic acid

The microbial substrate for urolithin formation. Conversion depends on the community and can stop at intermediates. It is not urolithin A.

Tyrosol

Phenolic compound in olive oil; neuroprotective effects and precursor to hydroxytyrosol

docs > substances > bioactive-compounds > polyphenols > secoiridoids

Oleacein

Secoiridoid polyphenol in extra-virgin olive oil; antioxidant and NRF2 activation

Oleocanthal

Secoiridoid polyphenol in extra-virgin olive oil; NF-κB inhibition and anti-inflammatory effects

Oleuropein

Major secoiridoid polyphenol in olive oil; oleuropein aglycone supports mitophagy, SIRT1, and AMPK activation

docs > substances > bioactive-compounds > terpenes > diterpenes

Carnosic acid

Rosemary diterpene linked to antioxidant and anti-inflammatory signaling in preclinical models.

Carnosol

Rosemary diterpene with anti-inflammatory and anti-cancer mechanistic evidence from preclinical literature.

docs > substances > bioactive-compounds > terpenes > monoterpenes

Carvacrol

Thymol isomer in thyme and related Lamiaceae herbs; chemotype-dependent.

Thymol

Phenolic monoterpene that defines thyme aroma; concentration varies by chemotype and drying.

docs > substances > bioactive-compounds > terpenes > phenylpropanoids

Cinnamaldehyde

Key aromatic compound in cinnamon; supports glycemic control and insulin sensitivity