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BRS3(KC1) - Antioxidant Substrate Sufficiency
1. Ambition
Maintain antioxidant substrate sufficiency so endogenous redox buffering and glutathione-linked protection remain stable under inflammatory demand.
2. Shared Biological Pool
- Polyphenols ← berries, cocoa, green tea
- Vitamin C ← citrus, kiwi, bell peppers
- Cysteine ← eggs, poultry, legumes
- Glycine ← collagen-rich cuts, poultry, legumes
- Glutamate ← meat, fish, soy
3. Biological Importance
This pool combines direct antioxidant compounds with glutathione-building amino-acid substrates that support endogenous defence systems. Together they sustain redox buffering, antioxidant recycling, and glutathione-linked protection. Insufficiency across either component increases vulnerability to oxidative damage across multiple inflammatory and antioxidant mechanisms.
4. Connected Mechanisms
Functional Mechanisms
Primary Mechanisms
- BRS3-FM1-PM1 - NF-kB Signalling Regulation
- BRS3-FM2-PM3 - Nrf2-ARE Antioxidant Activation
- BRS3-FM2-PM4 - ROS Generation vs Clearance Balance
- BRS3-FM2-PM5 - Lipid Peroxidation Control
- BRS3-FM1-PM2 - Gut-Derived Inflammatory Signalling
- BRS3-FM2-PM6 - Antioxidant Network Recycling