BRS3 - Inflammation & Oxidative Stress
Immune and redox regulation layer covering inflammatory signalling and oxidative balance.
Immune and redox regulation layer covering inflammatory signalling and oxidative balance.
Xanthophyll carotenoid in salmon, salmon roe, and related marine foods; mapped to BRS3 redox signalling and BRS4 mitochondrial membrane protection.
Essential methyl-donor nutrient in eggs, meat and milk; mapped to BRS2 one-carbon metabolism and BRS6 hepatic lipid export.
Endogenous redox-sensitive cofactor for aromatic-amino-acid hydroxylases and nitric-oxide synthases; not a dietary vitamin or food bioactive.
Endogenous γ-glutamyl-cysteinyl-glycine tripeptide and GSH/GSSG redox resource pool; nutritionally relevant through precursor supply, synthesis and recycling rather than as a vitamin.
Principal sesame lignan; preliminary cardiometabolic trials, null food-level findings, and incomplete translation to ordinary servings.
Distinct sesame lignan with redox and neuroprotective laboratory findings and almost no human clinical evidence.
Reactive organosulfur compound formed when garlic is crushed; linked to antioxidant and antimicrobial effects.
Isothiocyanate formed from glucoraphanin when myrosinase is active; studied for Nrf2 signalling.
Dietary flavonol in leafy greens, herbs, tea and some fruits; studied as a food constituent and as an isolated hormetic/senolytic agent.
Key SCFA supporting mitochondrial function, gut barrier integrity, and neuroinflammation reduction
Microbiome-derived metabolite from ellagitannins; supports mitochondrial resilience and mitophagy
Nonessential amino acid in collagen-rich foods. Substrate of glutathione assembly. Trials of glycine taken alone report psychiatric-symptom changes and small, high-bias sleep findings.
Essential cuproenzyme cofactor for catecholamine synthesis, iron efflux and redox defence; mapped to BRS1, BRS3, BRS5 and BRS6.
Cofactor in neurotransmission and antioxidant enzymes; dopamine modulation