14 docs tagged with "Methylation & One-Carbon Metabolism"

Biochemical regulation layer for one-carbon metabolism, methyl donor flux, and related mechanisms.

Trimethylglycine in beets, spinach, wheat germ and quinoa; methyl donor for BHMT, with brain effects not yet established.

Essential methyl-donor nutrient in eggs, meat and milk; mapped to BRS2 one-carbon metabolism and BRS6 hepatic lipid export.

Endogenous redox-sensitive cofactor for aromatic-amino-acid hydroxylases and nitric-oxide synthases; not a dietary vitamin or food bioactive.

Endogenous γ-glutamyl-cysteinyl-glycine tripeptide and GSH/GSSG redox resource pool; nutritionally relevant through precursor supply, synthesis and recycling rather than as a vitamin.

Supplemental cysteine precursor. The glutathione result used it together with glycine in older adults. It is not food cysteine.

Nucleoside that can supply CTP for CDP-choline. UMP and uridine-plus-DHA combinations are separate exposures.

Sulfur amino acid made from methionine. Food tables report cystine. Mapped to glutathione assembly with the formula-diet limits.

Amino acid and the substrate of GAD and of the first step of glutathione assembly. Intracellular roles are not a requirement to eat glutamate.

Nonessential amino acid in collagen-rich foods. Substrate of glutathione assembly. Trials of glycine taken alone report psychiatric-symptom changes and small, high-bias sleep findings.

Amino acid condensed with homocysteine by cystathionine beta-synthase. Diet and endogenous synthesis can both supply it.

Cofactor in neurotransmission and antioxidant enzymes; dopamine modulation

A reduced form of vitamin B9 in foods, and the methyl donor for homocysteine remethylation.

Methylation; myelin; mitochondrial odd-chain FA metabolism