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BRS1(FM2) - Glycaemic Modulation of Neurotransmitter Balance
1. Definition
Influence of carbohydrate quality, meal sequencing, and glycaemic response on precursor partitioning and neurotransmitter bias.
2. Functional Outcome Context
These outcomes describe translational contexts for the FM as an integrated biological capacity. They are not single-mechanism treatment claims. Confidence may increase where multiple child PMs converge on the same functional outcome.
No functional outcome context currently mapped.
3. Intervention Breakdown
Food-State Dominant
4. Functional Role
↑ insulin-mediated LNAA partitioning context; ↑ serotonin/catecholamine bias control; ↑ glucose stability
5. Mechanistic Basis (Integrated FM Narrative)
Glycaemic modulation of neurotransmitter balance emerges from the coordinated interaction of several primary mechanisms and supporting biological pools.
5.1 Core Primary Mechanisms
- BRS1-FM2-PM3 — LAT1 Competitive Transport Modulation Meal composition shifts large neutral amino-acid (LNAA) competition at the blood–brain barrier LAT1 transporter and alters precursor entry conditions.
5.2 Supporting Biological Pools (Key Constraints)
- None listed
5.3 Integrated Functional Narrative
Together, these PMs operationalise BRS1(FM2) as coordinated glycaemic modulation of neurotransmitter balance.
6. Connected Mechanisms
- None listed