ALA (Alpha-Linolenic Acid)
Essential omega-3 precursor; limited conversion to DHA/EPA
Essential omega-3 precursor; limited conversion to DHA/EPA
Accounts for ~10–15% of total brain fatty acids, 20–30% of neuronal phospholipids (PE, PS), and >90% of brain omega-3 PUFA; critical for membrane fluidity, synaptic vesicle fusion, neurodevelopment
The "intermediate" between EPA ↔ DHA; important in vascular health, repair, and immune modulation
Potent anti-inflammatory; precursor to E-series resolvins; modulates dopamine and serotonin signalling
(EPA, DHA) Anti-inflammatory, membrane, and neuromodulatory lipids central to BRAIN Diet
Omega-6 PUFA; eicosanoid precursor; balance with omega-3s
Essential omega-6; precursor to arachidonic acid and eicosanoids