9 docs tagged with "Endocannabinoid System"

Cross-system endocannabinoid signalling spanning neurotransmission, inflammation, metabolism, and gut-brain integration

Acetylcholine precursor; methyl donor; phospholipid synthesis for membranes

Soy isoflavone; ECS modulation via FAAH inhibition; anti-inflammatory/neuroprotective

Brain phospholipid; precursor to PC and NAPE → NAEs (PEA/OEA/AEA)

Accounts for ~10–15% of total brain fatty acids, 20–30% of neuronal phospholipids (PE, PS), and >90% of brain omega-3 PUFA; critical for membrane fluidity, synaptic vesicle fusion, neurodevelopment

Potent anti-inflammatory; precursor to E-series resolvins; modulates dopamine and serotonin signalling

(EPA, DHA) Anti-inflammatory, membrane, and neuromodulatory lipids central to BRAIN Diet

Nutritional strategies targeting HPA axis regulation, stress response, neurochemical balance, and gut-brain communication to reduce anxiety and support emotional regulation

Food-first dietary interventions targeting neurochemical balance, inflammation, gut-brain axis, and metabolic health to support mood regulation and emotional resilience